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Overview of Causes of Kidney Failure in Children


2013-03-06 14:46

Overview of Causes of Kidney Failure in ChildrenFor general population, slightly more than 30 individuals in every 100,000 develop Kidney Failure per year. In the pediatric population (age ≤19), the annual rate is 1 or 2 new cases in every 100,000 children. The risk increases steadily with age. Below is an overview of some of the common causes of Kidney Failure in children.

Acute Kidney Disease

This may be caused due to an injury or poisoning. Any injury that leads to loss of blood may decrease renal function temporarily, but once the blood supply is replenished, the kidneys often return to normal.

•Hemolytic uremic syndrome. This condition mostly affects kids under 10 years of age. It is the leading cause of acute renal failure among children. Most cases, however, return to normal after a few weeks. Only a small percentage of kids will develop CKD.

•Nephrotic syndrome. A child with this syndrome will experience urinating less often, swelling (around the eyes, legs, and belly), high levels of protein in urine, etc. Usually, the kid can eventually return to normal with no lasting kidney damage with treatment of prednisone.

Chronic Kidney Disease

• Birth defects. Some babies are born without kidneys or with abnormally formed kidneys.

• Blocked urine flow and reflux.

• Hereditary diseases such as Polycystic Kidney Disease, Alport syndrome, etc.

• Glomerular diseases. Some diseases that severely attack the filtering units of the kidneys - glomeruli, may result in Kidney Failure.

• Systemic diseases such as Diabetes, Lupus, etc.

Unfortunately, these conditions cannot be easily fixed. Usually, the condition will develop so slowly that it goes unnoticed until permanent damage of the kidneys. Eventually, dialysis or kidney transplant has to be adopted with Kidney Failure.


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