Diabetes is hard to manage. You can get a comprehensive understanding of the disease here and get the information about the latest treatments and get professional advices. read more

Micro-Chinese Medicine Osmotherapy is a brand-new therapy based on traditional Chinese herbal medicines dating back thousands of years ago. It combines the essences of herbal medicines read more

Hormonal therapy is commonly used to treat Kidney Disease in clinic. It refers to use one or more than one hormone medicines to suppress the over-reactive immune reaction read more

Patients are suggested to treat kidney disease first before they get pregnant read more

If you are diagnosed with Kidney Disease, you should talk to your doctor about starting an exercise read more

Foods and Drinks play an important role in Kidney Disease patients read more

Kidney Disease News and Events read more

In every week, a famous experienced renal medicine specialist will be invited to help diagnose and evaluate inpatient's disease condition, offering detailed therapeutic schedule. read more

Word Kidney Day Font Size A A A

Relationship between Hypertension and Chronic Allograft Nephropathy

Provided by Expert Zhang Youkang on 2012-09-18 16:55

Chronic Allograft Nephropathy (CAN) is one of the most common cause of kidney transplant loss. The pathogenesis of CAN is complex and incompletely understood, and involves several immunological and non-immunological factors. Here, we talk about the relationship between hypertension and CAN.

1. Hypertension is a risk factor for Chronic Allograft Nephropathy.

For long time, it has been known that high blood pressure is associated with graft failure. High blood pressure of the recipient is one of the non-immunological causes of CAN. The graft survival was significantly inferior in hypertensive patients.

2. Is hypertension the cause or consequence of CAN?

The association between high blood pressure and deterioration of kidney function isn't proved to be a causal relationship. Hypertension after kidney transplant may simply be the result of graft function deterioration rather than vice versa. Studies can not differentiate between cause and effect of the relationship between high blood pressure after transplant and graft survival.

The first evidence that hypertension per se may result in graft damage was the observation that not only elevated blood pressure after kidney transplant, but also increased blood pressure before transplantation is related with later CAN. In the latter cases, the risk can be icnreased by a factor of 3.4, the magnitude which was only surpassed by late (>60 days after transplantation) acute rejection episodes, which increased the risk by 5.5. Studies in animals also support the concept of hypertension-induced graft damage.

Recognizing the association between hypertension and CAN can help patients better deal with their conditions. Is there still anything unclear? You can leave us a message or contact our online family doctor.

If you send us email, please leave your phone number or WhatsApp/Viber (with country code) in email so that our renal expert can communicate with you timely and directly. We will do utmost to help you solve the problems.

What else you want to know:
Make An Appointment Beijing Tongshantang Hospital of Traditional Chinese Medicine.
How can I get this treatment?
How can I get this treatment in my countries?
How much does this treatment cost?
What is the duration if I receive this treatment in your hospital?
What should I prepare to your hospital except visa?
How can I go to your hospital?

(+area code)Phone Number:
Whatsapp :
Disease Description:
contact us
patient story

Patient Story

Latest Articles