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Top Facts on Goodpasture Syndrome


2013-02-02 17:21

Goodpasture syndrome is an autoimmune disorder which can involve both kidneys and lung. Knowing more about it can help you control the condition better. Here are top 10 facts about goodpastrure syndrome.

What causes the disease?

Goodpasture syndrome may be an inherited condition, or occurs due to a combination of factors.

What are the symptoms of goodpasture syndrome?

It can cause serious bleeding in the lungs. Damage to kidneys is very severe and can lead to kidney failure. If kidney function is affected, it will lead to the following symptoms:

* Proteinuria

* Blood or proteins in urine

* Frequent urination at night

* Burning sensation during urination

* Swelling in hands or feet

* High blood pressure

* Nausea or vomiting

How is the disease diagnosed?

1. Blood test is performed to see if there is harmful antibody in blood.

2. Renal biopsy is used to see if the kidney tissue is damaged by the antibody.

What is the prognosis of goodpasture syndrome?

Usually, the production of antibodies in body will last for several weeks to years. Once this stop, you should not have any more problems with your lungs. However, your kidneys may have damaged a little or a lot. It is reported that five year survival rate is 80%. In less than 30% cases, people need long-term dialysis treatment.

Is goodpasture syndrome inherited?

In rare cases, it can be inherited. There are a few cases where more than one family has the disease.

What are the complications of the disease?

* Chronic kidney disease (CKD)

* End stage kidney disease

* Rapidly progressive glomerulonephritis

* Severe lung bleeding

What are the treatments of goodpasture syndrome?

1. Plasmapheresis is used to remove the harmful antibodies from blood.

2. Corticosteroid medications and other drugs are used to suppress immune system.

3. Controlling high blood pressure is important to delay kidney damage.

4. It is important to change diet. A diet low in salt and proteins is required.

5. If kidney damage is serious, dialysis or kidney transplant is required.

6. Immunotherapy is the latest treatment for goodpasture syndrome. It can eliminate the cause of the disease and control the condition completely.




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