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How To Help CKD Slow The Process Of Uremia


2019-02-19 10:32

Process Of Uremia,CKDMost patients with nephropathy have normal renal function. Most of them have urinary protein, urinary occult blood, and some are renal failure patients with elevated serum creatinine. When the glomerular filtration rate decreases year by year to below 15 ml/min, the residual renal function is insufficient to maintain human life activities, and it becomes uremia.

Human kidneys, with 2 million renal units, will be necrotic due to overnutrition, environmental pollution, work fatigue and other reasons. Normally, after 40 years of age, the glomerular filtration rate will decrease by 1 ml/min per year (the normal value is about 120 ml/min).

Nephron units in patients with nephropathy are accelerated by nephritis, diabetes mellitus, hypertension, hyperuricemia, infection, nephrotoxic substances, heredity and gene mutation. For example, in patients with chronic glomerulonephritis and nephrotic syndrome progressing to uremia, the annual decline rate of glomerular filtration rate of 3-5 ml/min is relatively common. In patients with acute renal failure, the filtration rate will drop by tens of units within a week.

The number of uremic patients in developed countries has been declining in recent years after decades of sustained growth. Although nephropathy is difficult to treat, most patients can be relieved after treatment, and a small number of patients with poor pathology, more complications and rapid progress of renal function can also be controlled.

How To Help CKD Slow The Process Of Uremia?

1. Patients with urinary protein above 0.5g/24h may consider using pril/sartan drugs and traditional Chinese medicine to reduce urinary protein, improve renal environment and protect renal function.

2. Patients with proteinuria more than 1g/24h should be examined and diagnosed in detail, and the pathological type should be defined. Hormones and immunosuppressants can be used to control inflammation and reduce proteinuria.

3. In patients with urinary protein over 3.5g/24h, besides urinary protein, attention should also be paid to the prevention and treatment of complications, such as thrombosis and embolism, water and sodium retention, pleural and peritoneal effusion, etc.

4. Nephrotic patients should eat a low-salt diet with a daily salt intake of 3-6g. Low-salt diet can reduce blood pressure by 5-10 mmHg and urinary protein by 20%.

4. Nephrotic patients with hypertension should use pril/sartan drugs, which can be combined with horizon drugs to reduce blood pressure, and try to control the whole day blood pressure below 130/80 mmHg. The goal of lowering blood pressure for the elderly over 65 years old can be relaxed appropriately. Blood pressure should be measured at home every day, regular feedback and communication with doctors to adjust antihypertensive drugs.

5. Metformin is the first choice for diabetic patients with nephropathy, followed by repaglinide, nateglinide, acarbose, voglibose, liraglutide and exenatide. Glipizide, gliclazide and other sulfonylureas as well as insulin sensitizers such as rosiglitazone and pioglitazone should be avoided as far as possible.

6. For nephropathy patients with hyperlipidemia, patients with elevated cholesterol were treated with statins (also with the effect of lowering urinary protein), while patients with elevated triglycerides were treated with beta drugs.

7. Patients with hyperuricemia should have a low purine diet. Allopurinol and febupropathrin are the first drugs to inhibit the production of uric acid, followed by benzbromarone and other drugs to promote the excretion of uric acid, so as to avoid the impairment of renal function caused by the increase of uric acid.

These seven methods are not very difficult, but most patients with nephropathy did not do it because they did not know it, and a few patients have been diagnosed.

Patients with renal failure need comprehensive treatment. Anemia patients should use erythropoietin, iron or appropriate amount of red meat to supplement iron to improve anemia; hyperkalemia patients should eat low potassium diet, adjust blood potassium drugs, glucose solution to reduce blood potassium; acidosis patients should supplement alkali (sodium bicarbonate) treatment, and do a good job in monitoring blood pressure and electrolytes.

If the clinical treatment is in place, combined with the cultivation of good living habits such as "five low and one high" diet, smoking cessation, alcohol cessation and physical exercise, and take Chinese Medicine Treatment. We believe that the incidence of uremia will drop dramatically and patients will become fewer and fewer.

If you want to know more information, please leave a message below or send the medical reports to us. We will try our best to help you.

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