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Goodpasture Syndrome Symptoms


2013-02-02 16:48

Goodpasture syndrome is an autoimmune disorder. It occurs when the immune system can not function normally and attacks healthy body cells and tissues mistakenly. This syndrome can involve both of kidneys and lungs and mainly presents the following symptoms.

Symptoms may occur very slowly over months or even years, but they often develop very quickly over days to weeks.

Early symptoms of goodpasture syndrome include fatigue, nausea, difficult breathing and the pallor.

As the condition progresses, when the lung is involved, it will cause the following symptoms:

* Hemoptysis is one of symptoms of goodpasture syndrome. The level of hemoptysis may vary and, in a small percentage of patients, may be absent. Cough, dyspnea, and shortness of breath are commonly seen in pulmonary symptoms.

* Respiratory failure may occur due to massive pulmonary hemorrhage.

* Less than 50% of cases develop chest pain.

* Significant anemia may result from persistent intrapulmonary bleeding.

Eventually, kidneys are involved, the symptoms of kidney involvement in goodpasture syndrome include:

* Protein in urine is one of common symptoms of goodpasture syndrome. It occurs as the filtering units of the kidneys are impaired.

* Small amount of blood in the urine due to leakage of red blood cells through glomeruli.

* High blood pressures occurs due to retention of fluids in body.

* Eventually uremia occurs.

The above are the common symptoms of goodpasture syndrome.The long outcome of the condition is not good so aggressive treatment should be used early.Immunosuppressive medications, corticosteroids and plasmapheresis general treatments for goodpasture syndrome. However, they are not enough to control the condition. Immunotherapy is the latest treatment for goodpasture syndrome. It can treat the condition from the root causes and stop the disease completely. Therefore, it can stop the condition from developing renal failure completely.


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