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How to Treat High Blood Pressure in CKD


2013-09-22 17:20

High blood pressure caused by CKD is also called renal hypertension, and it is a big risk for CKD patients. More than 80% of CKD patients have this disease in their end stage kidney failure. Do you know how Chronic Kidney Disease leads to high blood pressure and how to treat it?

Causes of high blood pressure in CKD

There are two causes of high blood pressure. One is renal vascular hypertension, and the other is renal parenchymal hypertension.

● Renal vascular hypertension. The function of renal glomeruli is to filter the blood that flow through it. When it is damaged, the kidney loses the function of excreting sodium and water from the body. This can lead to the retention of water and sodium. Water and sodium retention causes the thicken of vessel wall and at the same time enlarges the amount of blood, hence lead to high blood pressure.

● Renal parenchymal hypertension. Diseases of renal parenchyma make the juxtaglomerular cells release a lot of renin. Too much renin constricts the vessels and hence increases blood pressure. Renin and angiotensin increase the amount of aldosterone secretion, thus causing water and sodium retention. Water and sodium retention make further increase of blood volume, thus aggravating hypertension.

How to treat high blood pressure in CKD?

Since the risk of high blood pressure is so dangerous, we must control it immediately. Here, some treatments are helpful.

Renovascular hypertension. The leading treatment of renovascular hypertension is surgery, including nephrectomy, renal vascular remodeling percutaneous transluminal renal angioplasty, as well as renal artery stent angioplasty. Medicine treatment is not the preferred method for renovascular hypertension. Patients use medicine treatment only when they are not fit surgery. Medicines they use include beta-blockers, calcium channel blockers, and so on.

Renal parenchymal hypertension. The main leading treatment is to interdict renin-angiotensin system. ACEI and Ang Ⅱ receptor antagonist medicine are two main medicines to interdict RAS.

All these medicines mentioned are of good effect and have little burden on kidneys of CKD patients. Sometimes you have to take several different kinds of medicines to strengthen the effects of medicines. Therefore, when you take medicines, ask your doctor and pay attention to the dosage of these medicines. If you have any questions, ask our free online doctor.


If you send us email, please leave your phone number or WhatsApp/Viber (with country code) in email so that our renal expert can communicate with you timely and directly. We will do utmost to help you solve the problems.



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