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Herbal Treatment for CKD--Astragalus

2012-10-03 16:51

Herbal Treatment for CKD--AstragalusAstragalus is a kind of traditional Chinese herbal medicines. Some studies show that this herb plays an important role in slowing CKD progression.

Chinese herbal medicine has renoprotective effects. They can reduce proteinuria and improve dyslipidaemia. Meanwhile, they can suppress the inflammation in kidneys and correct immune system by inhibiting the overproduction of TGF.

Astragalus has showed the following curative effects in treating CKD.

Reduction of proteinuria

In most cases of CKD, it is associated with proteinuria. Proteinuria is not only a marker of significant renal injury, but also as a contributor to renal pathologic injury itself. Astragalus can reduce proteinuria by suppressing inflammatory response in kidneys.

Amelioration of dyslipidaemia

Lipid metabolism disorders can enhance the renal injury in CKD. Astragalus not only can improve edema and lower proteinuria, but also can reduce serum total cholesterol,triglyceride, low-density lipoprotein and very low-density lipoprotein levels. The herb can achieve this curative effect by regulating the gene expression of hepatic LDL-receptor and an increase in the activities of serum lipoprotein lipase and lecithin cholesterol acyltransferase.

Regulation of immune system

Astragalus has a beneficial effect in regulating immune system for people with CKD. It can strength the activity of natural killer cells and reduce the production of other cytokines such as IL-1,IL-6 and IL8.

Protective effects against renal damage

Astragalus shows effects in slowing slowing the progression of renal interstitial fibrosis. In this way, it can retard CKD progression.

Diuretic effects

Diuretics are effective in treating expanded blood volume, but a myriad of adverse effects can not be avoided. Astragalus is effective to improve retention of water and sodium. This is beneficial to improve cardiac and renal function for CKD patients.

Some herbal medicines may cause harm to body if they are not used in certain amount. Therefore, the patients with CKD should never take herbal medicine randomly without the permission of a practitioner.

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