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Treatment Options for Recurrent FSGS after Kidney Transplant


2013-04-12 16:14

Kidney transplant is a preferred treatment option for people with kidney failure.It is a major procedure in which the diseased kidney is replaced with a healthy kidney.If the body adjust to the new kidney, the patients can live a normal life.However,recurrence rate of FSGS after kidney transplant is very high,approximately 30% recurrence rate after first transplant.What are the treatment options for recurrent FSGS after kidney transplant?

Plasma exchange

FSGS occurs due to abnormal activity of immune system which can cause immune complexes in blood. So the abnormal immune system also can attack the transplanted kidney to cause kidney damage.Thereby, some cases of recurrent FSGS after kidney transplant can be treated with plasma exchange.When the treatment is perfromed,the plasma with hamrful substances is repalced with fresh plasma or other substitue. This therapy can help relieve activity of immune system to slow the disease progression.

Cyclosporine

Cyclosporine has been reported to be effective in reducing proteinuria caused by recurrent FSGS after kidney transplant.The anti-proteinuric effect of cyclosporine may be attributed both to suppression of T cells and inhibited production of their cytokines. However, use of cyclosporine can cause many adverse effects. Some ways can help you minimize the side effects. You can email to kidenyabc@hotmail.com  to get the detailed information about those ways.

Dialysis

Due to ineffeiciency of treatment modalities,when the transplanted kidney fails,the patients have to return to dialysis until next kidney transplant become available. However, life on dialysis is really tough.

Kidney transplant

The patients with recurrent FSGS still have the opportunity to get another kidney transplant. However, the recurrence will become higher if the patients have allograft failure before. The recurrence rate can as high as 80% in the second transplant.

Immunotherapy

Early aggressive treatment can help the patients with recurrent FSGS avoid kidney failure.Immunotherapy is an alternative treatment for the patients. This therapy can correct the abnormal immune system to stop it from attacking the transplanted kidney further. Also, it can help the body resume the self-healing ability of body to promote the self-regeneration of the impaired kidney tissues. Thus, it can bring an improvement in renal function.

The above are the treatment options for recurrent FSGS after kidney transplant. You can choose the right treatment based on your own condition.



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