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Treatment for Recurrent FSGS After Kidney Transplant

2013-12-05 09:19

Treatment for Recurrent FSGS After Kidney TransplantSome patients may think that after kidney transplant they will live healthily. But the fact is that FSGS may recur. It is reported that FSGS recurrence rate averages about 30 percent. Why does FSGS recur after kidney transplant? If it recurs, how to treat it?Today you may find the answers here.

Why does FSGS recur after kidney transplant?

FSGS recurrence may be related to viral infection, toxin exposure, genetic mutation, and obesity. In addition, FSGS may develop as a result of hyperfiltration injury related to loss of functioning kidney parenchyma. The fundamental reason why FSGS recurs is that the blood in the kidneys is polluted. Though the damaged kidney is replaced, the polluted blood around remains there. You may wonder that before kidney transplant dialysis has helped to filter these wastes and toxins in the blood, why I say blood is still polluted. Dialysis can only filter some small molecule wastes, but the macromolecular substances, such as pathogenic factors, are still there. Therefore, it is not enough to transplant a new kidney and to clear the polluted blood is also necessary.

Treatment for recurrent FSGS after kidney transplant

There is no consensus on the optimal treatment of recurrent FSGS. Plasmapheresis is often employed in the treatment of recurrent FSGS in kidney transplant, where it appears to be effective in the pediatric population. Immunothrapy may be also a wise choice, which can not only clean the pathogenic factors and wastes in the blood through various blood purification measures, but also prevent kidney sclerosis and improve kidney function.

FSGS recurrence becomes one of the reasons which lead to the failure of kidney transplant. So attention must be paid after kidney transplant to your new kidney. Regular physical condition examination can help you have a good knowledge of your state of illness. Besides, keeping a healthy lifestyle also plays an important role in preventing FSGS recurrence.

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