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Do Antihypertensives Cause Raised Creatinine Levels


2013-11-24 15:58

Do Antihypertensives Cause Raised Creatinine LevelsGenerally speaking, almost all drugs have side effects. For patients with high blood pressure, antihypertensives are necessary for them to control high blood pressure. Suffering from high blood pressure for a long time, patines may begin to concern about the consequence brought about by the antihypertensives. The problem troubles them the most is whether antihypertensives cause raised creatinine levels or not.

Why do creatinine levels raise?

Creatinine levels are often associated with kidney disease. Kidney is responsible for filtering metabolic wastes in the blood. When kidney function compromises, the wastes in the blood such as creatinine will build up in the blood, leading to raised creatinine levels.

Do Antihypertensives Cause Raised Creatinine Levels?

-Angiotensin converting enzyme inhibitors (ACE inhibitors) are the common drugs to treat high blood pressure. They have the function of blocking information of a hormone that causes blood vessels to narrow, so vessels relax. A limited elevation in serum creatinine level may seen when you first eat ACE inhibitor. However, when you stop taking the drug, raised creatinine levels will return to normal.

-Other antihypertensives including diuretics, beta-blockers, angiotensin II receptor blockers (ARBs), calcium channel blockers(CCBs), alpha-blockers, alpha-2 receptor agonist, alpha-beta-blockers, central agonists etc.They all have many side effects. But under normal circumstances they do not cause raised creatinine levels.

High blood pressure is the secondary factor to kidney disease than diabetes. If these antihypertensives have no effect on your high blood pressure, your kidney will be damaged when the blood vessels are exposed to high blood pressure for a long time. As a result, creatinine in the blood can not be discharged out of body.

Therefore, you should take a good care of yourself when you have high blood pressure. An effective antihypertensive has much relationship with the your physical condition, or hypertensive nephropathy is more likely to follow you.


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