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Life Span of People with IgA Nephropathy And Nephrotic Syndrome

2013-05-06 11:34

IgA nephropathy is a kind of glomerulonephritis featured with antibodies(immunoglobulin A) in kidneys.As the disease progresses, it can lead to a number of symptoms and complications.Nephrotic syndrome can occur in some cases of IgA nephropathy.IgA nephropathy with nephrotic syndrome often indicates a poor prognosis.Then what is the life span of people with IgA nephropathy and nephrotic syndrome?

There is no a standard answer to their life span.But it is sure that renal function decline more rapidly among IgA nephropathy people with Nephrotic Syndrome than those without nephrotic syndrome.

The life span of people with IgA nephropathy and nephrotic syndrome varies from individual to individual due to the following attributable factors.

Protein in urine

Protein in urine is a significant accelerator of renal function.In general, if protein in urine is above 1 g in a day, it indicates a poor prognosis. The higher levels of protein in urine, the worse the prognosis of the disease.

High blood pressure

High blood pressure is one of common symptoms of IgA Nephropathy and also can affect the disease progression a lot. As high blood pressure can put extra strain on kidneys, it can cause kidney function to decline more rapidly and also can increase the leakage of protein in urine. Keeping blood pressure level at 130/80 can improve the outcome of the disease.


It is widely known that most of the patients with Kidney Disease die of complications of the disease before kidneys fail completely.Therefore, complications can affect the life span of people with IgA nephropathy and nephrotic syndrome significantly.Cardiovascular disease is a major death cause of people with kidney disease.


Treatment plays the most important part in affecting the life span of people with IgA nephropathy and nephrotic syndrome.Besides general treatments such as steroids, immunosuppressive agents, blood pressure medications etc, an alternative treatment is suggested to the patients. It is immunotherapy.

Immunotherapy can treat IgA nephropathy from its causes.It can correct stop abnormal immune response and rebuild normal immune system. Thus, it can stop the disease progression completely. If so, the patients with IgA nephropathy and nephrotic syndrome will be able to have a normal life span.

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