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Latest Treatment for Berger's Disease


2013-02-06 10:38

Berger's disease is also known as IgA Nephropathy. It occurs when an antibody called immunoglobulin A (IgA) lodges in your kidneys. This can affect the normal filtering ability of your kidneys. Over time, it can lead to a myriad of symptoms including hematuria, proteinuria, high blood pressure and swelling. Although some people with Berger’s disease can get a complete remission, others eventually develop end stage renal disease (ESRD). Early and aggressive treatment is required to stop the progression of the condition.

The routine treatment options for Berger's Disease are as follows:

* High blood pressure medications: ACE inhibitors or ARBs are used to treat high blood pressure. Meanwhile, they also can help reduce the amount of protein in your urine.

* Immunosuppressants: Corticosteroid medications such as prednisone, and other potent immunosuppressants can suppress immune system and help protect your kidney function.

* CellCept: It medication is used by the patients who have persistent protein in urine.

* Dialysis or kidney transplant: Kidney dialysis or even a kidney transplant may be necessary.

The routine treatment for Berger’s Disease only can control the symptoms of the condition and slow its progression. However, they are not enough to manage the condition well since they can not eliminate the causes of Berger’s Disease.

Berger’s Disease occurs due to immune dysfunction. IgA is a kind of antibody and defends against infection normally. However, in Berger’s Disease, it lose its normal role, but attacks healthy kidney cells and tissues by mistake. The deposit in kidneys can cause inflammation of kidneys to impair the kidney structure and then worsen renal function.

Therefore, to treat Berger’s Disease effectively, two important treatment steps are to remove the immune deposits and correct immune system.

Immunotherapy is the latest treatment for Berger’s Disease. This therapy can treat the condition from its causes and stop further kidney damage completely.




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