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Treatment for Berger's Disease in Children

2013-08-26 11:40

Berger’s disease is also called IgA nephropathy and usually occurs in people less than 30 years old.What is the recommended treatment for Berger's disease in children?

Berger's disease

Berger’s disease is an autoimmune disorder featured with deposits of proteins called antibodies in glomeruli.Antibodies are normally made by the immune system to fight infections. However,in Berger's disease, the immune system fails to work normally,causing these antibodies to deposit in glomeruli.The unwanted deposits of proteins will result in inflammatory response in kidneys.If the inflammation can not be controlled, it will cause progressive renal function deterioration. Eventually, Kidney Failure will occur.

Treatment for Berger's disease in children

The general treatment for Berger’s disease in children mainly focuses on controlling blood pressure and reducing protein loss in the urine.ACE inhibitors are classic blood pressure medicines and also are effective in controlling protein in urine.Fish oil sometimes is used to suppress the inflammation in kidneys. Immunosuppressive agents are used to suppress the excessive inflammatory response in kidneys.The above treatment for Berger’s disease in children can slow the disease progression to some extent.However,the medicines may bring some side effects and also can not control the relapse of the disease.

Latest treatment for Berger's disease in children

Immunotherapy is the latest treatment for Berger’s disease in children.It can treat the disease from its underlying causes so it can bring about a remarkable improvement.It works in the following ways to treat Berger's disease.

Firstly,it can suppress the inflammatory response to stop further immune damage to kidneys.

Secondly,it can degrade the deposits in kidneys to eliminate the triggering factors of inflammation in kidneys.

Thirdly,it can rebuild the immune system in body and self-healing system.When impaired kidney tissues are regenerated, the renal function will have an improvement.

If the accelerators and causes of renal function deterioration are controlled fundamentally, the patients will avoid developing kidney failure completely.

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