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What Kind of Dialysis Is Best for IgA Nephropathy Patients


2013-09-14 15:21

IgA Nephropathy is one kidney disease characterized by predominant IgA deposition in glomerular mesangial area. When glomeruli in charge of filtering out waste products are damaged badly, kidneys can’t do their work well and then patients may need dialysis. Well then, what kind of dialysis is best for IgA Nephropathy patients?

Firstly, find out the root cause of IgA Nephropathy

When some foreign substances, called antigen, attack our body, our lymphocyte will produce humoral immunity and cellular immunity. During this process, some antibodies form to combine with antigens and protect our body. Normally, the combination of antigens and antibodies, called immune complexes, can be discharged from the body successfully. However, if the immune system becomes abnormal, these immune complexes are more likely to settle in the body.

IgA Nephropathy occurs when IgA deposits in the kidneys. After many years, the build up of IgA causes the kidneys to leak blood and sometimes protein in the urine. If untreated effectively, IgA Nephropathy is more likely to develop kidney failure.

Conventional dialysis for IgA Nephropathy

Hemodialysis and peritoneal dialysis are two common dialysis techniques. With the principle semipermeable membrane or peritoneum, patients’ blood and dialyzate can exchange substances. Metabolic wastes and excess electrolyte move to dialyzate from the blood, while calcium and some nutritions enter into blood. Therefore, hemodialysis and peritoneal dialysis can be used to maintain patients’ basic life.

However, these two dialysis techniques only can remove small molecular substances. As for moderate or big molecular substances like immune complexes, both hemodialysis and peritoneal dialysis can do nothing.

What kind of dialysis is best for IgA Nephropathy patients?

From the above analysis, we can know a dialysis that can remove not only metabolic wastes but also immune complexes is a good choice for IgA Nephropathy patients. Blood purification therapy which combines various dialysis techniques is able to eliminate both small molecular substances, just as conventional dialysis does, and immune complexes. What’s more, this therapy can also help repair damaged glomerular basement membrane. With the therapy, it is quite possible to make patients get rid of sustaining dialysis.

If you are suffering from end stage IgA Nephropathy, try to find a best dialysis for you with online doctor’s guidance. Any confusion or question, feel free to tell us.




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