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Slow Down IgA Nephropathy Development for 30 Years


2012-10-25 15:43

More than 70% of IgA Nephropathy will develop into Kidney Failure in 30 years. And about 20% of them may experience kidney failure even in 10 years. How to keep your IgA Nephropathy silent for more than 30 years?

Recently, treatment for IgA Nephropathy mainly focuses on the patient with high risk, that is, the patients who are prone to developing kidney failure within 10 years. How to figure out that you are in such a high risk or not? Doctor usually finds the “dangerous” patients at the basis of the severity of protein in urine, high blood pressure and kidney function decline etc.

And the conservative treatment is to use ACEI or ARB or other similar drugs to control your symptoms, such as to lower high blood pressure and decline the protein in urine, so as to slow down the course of IgA Nephropathy.

However, for the patients who may develop the kidney failure for more than 10 years, the doctor may just let them go or suggest some diet plan or exercise plan etc. Most patients of IgA Nephropathy develop the disease in their 20s. If the treatment only can expand their lifespan for 10 years, surely the treatment is failed.

How to make your lifetime longer?

The nephrologist, Reich, from Montreal, Canada, published his research named Remission of Proteinuria Improves Prognosis in IgA Nephropathy: in 542 patients, the kidney function decline average rate is 4.6ml/min. Among them, if the protein in urine <1g, 90% cases’ kidney function declines slowly than the average rate. If the protein in urine >3g, the kidney function decline speed is as fast as 25 times of the average speed.

Thereby, to control the protein in urine constantly and prevent the proteinuria relapse can delay kidney failure in a very large degree.

What makes the proteinuria relapse in IgA Nephropathy?

Proteinuria is a common symptom of IgA Nephropathy which usually comes back when you experience any cold or infections. In fact, IgA Nephropathy is caused by the underlying immune disorder in which any bacteria attack will trigger the failed immune system to releases excessive IgA and causes kidney damages.

This is why a mild cold or infection will call your proteinuria back. Thereby, to control IgA Nephropathy and delay the renal failure for 30 years, you are suggested to deal with your underlying immune system disorder firstly.




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