Diabetes is hard to manage. You can get a comprehensive understanding of the disease here and get the information about the latest treatments and get professional advices. read more

Micro-Chinese Medicine Osmotherapy is a brand-new therapy based on traditional Chinese herbal medicines dating back thousands of years ago. It combines the essences of herbal medicines read more

Hormonal therapy is commonly used to treat Kidney Disease in clinic. It refers to use one or more than one hormone medicines to suppress the over-reactive immune reaction read more

Patients are suggested to treat kidney disease first before they get pregnant read more

If you are diagnosed with Kidney Disease, you should talk to your doctor about starting an exercise read more

Foods and Drinks play an important role in Kidney Disease patients read more

Kidney Disease News and Events read more

In every week, a famous experienced renal medicine specialist will be invited to help diagnose and evaluate inpatient's disease condition, offering detailed therapeutic schedule. read more

Font Size A A A

What Are The Common Treatments For IgA Nephropathy


2019-03-03 13:52

IgA Nephropathy is the most common chronic glomerulonephritis. It is one of the main causes of uremia, which often occurs in naked hematuria after a cold.

Causes of IgA nephropathy

After infection of respiratory mucosa, gastrointestinal mucosa and genital mucosa, human body will produce a large number of glycosylated IgA1, which stimulates the abnormal immune system, forms immune complex, and induces immune inflammation in the kidney. This is IgA nephropathy.

IgA nephropathy caused by different infections has different severity. Some are asymptomatic hematuria, some are naked hematuria, some are mild albuminuria, some are massive albuminuria, some will be accompanied by hypertension, crescent formation, and eventually turn to uremia, some have no obvious symptoms throughout their lives, in a word, the difference is quite large. Hematuria with mild to moderate proteinuria is more common in clinic, 40% of patients with hypertension.

If the urinary protein exceeds 3.5g/24h, or if there is naked hematuria or hypertension, it indicates that the disease will progress faster, often within 10-20 years to uremia. If there is only a small amount of occult blood and urinary protein, the prognosis is generally better.

How should IgA nephropathy be treated?

1. Puli/sartan drugs

IgA nephropathy with hypertension often indicates poor prognosis and should be treated actively. Puli/sartan antihypertensive drugs should be the first choice for treatment. They can also reduce urinary protein while lowering blood pressure.

In most patients with IgA nephropathy with elevated blood pressure, one antihypertensive drug is often ineffective and requires combination of calcium antagonists (horizon antihypertensive drugs), diuretics and beta-blockers (Lol antihypertensive drugs).

2. Chinese Medicine

IgA nephropathy has not yet been treated with specific drugs. Many patients have not completely alleviated urinary protein after routine treatment. Generally, traditional Chinese medicine is needed for treatment. Patients can use traditional Chinese medicine after syndrome differentiation in large-scale Chinese medicine hospitals, which can improve marked efficiency.

3. fish oil

The effect of fish oil is not clear, but the side effects are small. Some IgA nephropathy patients have decreased urinary protein after taking fish oil. After 3 months of pralidol/sartan treatment, if 24-hour urinary protein level has not been reduced to less than 1 g, fish oil treatment may be considered. Generally, imported fish oil has higher purity and obvious efficiency. After taking, pay attention to monitoring urinary protein and serum creatinine to see if it is effective.

4. Hormones and immunosuppressants

If the 24-hour urinary protein of IgA nephropathy patients has not been reduced to less than 1 g after treatment with pril/sartan and traditional Chinese medicine, it is necessary to consider the use of hormones (prednisone) and/or other immunosuppressive agents to inhibit renal inflammation and alleviate proteinuria.

IgA nephropathy is generally not too sensitive to hormones, and its side effects are large, so it is necessary to carefully grasp the indications. "Low-dose hormone + leflunomide" is often better than hormone alone, and its side effects are smaller and safer.

5. Tonsillectomy

Tonsillectomy can alleviate clinical symptoms, reduce proteinuria and delay disease progression, but not all IgA nephropathy requires tonsillectomy, which needs to be weighed. If frequent tonsillectomy infection causes IgA nephropathy recurrence, tonsillectomy may be performed.

6. Other treatments

Most IgA nephropathy patients have low immunity and need antibiotics after bacterial infection.

Patients with edema need diuretic treatment. Thiazide diuretics (such as hydrochlorothiazide tablets) or loop diuretics (furosemide) can be used.

Patients with elevated cholesterol may use statins (such as atorvastatin or simvastatin).

Some diuretics and lipid-lowering drugs also have the effect of reducing urinary protein.

In conclusion, IgA nephropathy patients generally do not progress very fast, but lack of specific drugs, long-term uncontrollable prone to renal failure. Most patients need standard comprehensive treatment and follow-up once a month to 3 months. To avoid renal failure and uremia, we should keep communication with doctors and adjust drugs in time during treatment.

If you want to know more information, please leave a message below or send the medical reports to us. We will try our best to help you.

WhatsApp/Viber: +86 13503211882

Skype: abc.kidney

Email: kidneyabc@hotmail.com




If you send us email, please leave your phone number or WhatsApp/Viber (with country code) in email so that our renal expert can communicate with you timely and directly. We will do utmost to help you solve the problems.



What else you want to know:
Make An Appointment Beijing Tongshantang Hospital of Traditional Chinese Medicine.
How can I get this treatment?
How can I get this treatment in my countries?
How much does this treatment cost?
What is the duration if I receive this treatment in your hospital?
What should I prepare to your hospital except visa?
How can I go to your hospital?

Name:
Country:
(+area code)Phone Number:
Whatsapp :
Disease Description:
contact us

IgA Nephropathy

IgA Nephropathy Questionnaire
patient story

Patient Story

Latest Articles

Kidney Disease:
Information :
symptoms treatment
diet&fitness