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Five Kinds Of Kidney Disease Can Not Take Cold Medicine

2019-02-23 09:52

Take Cold Medicine,Kidney Disease,Most patients with nephropathy have low immunity and common cold. Non-steroidal anti-inflammatory drugs (NSAIDs) may be needed to alleviate symptoms when a cold occurs.

NSAIDs are a class of widely used drugs, including ibuprofen, aspirin, paracetamol, indomethacin, diclofenac, ketoprofen, naproxen, aminopyrine, celecoxib, rofecoxib, nimesulide, etc. They are commonly used for antipyretic and analgesic purposes. Most cold medicines available on the market contain these ingredients.

However, NSAIDs have certain renal toxicity.

This kind of kidney damage originates from two aspects:

One is that NSAIDs can constrict the arterioles entering the glomerulus and decrease the blood flow of the kidney. It is equivalent to pinching the neck of the kidney to make the kidney ischemic and hypoxic. Especially when fever, sweating and blood volume decrease, the changes of blood flow caused by drugs are more obvious, which may cause a series of kidney and systemic diseases.

Secondly, it can damage renal tubulointerstitium and lead to acute interstitial nephritis.

Therefore, NSAIDs are generally not recommended for nephrotic patients with low blood volume and poor renal function.

Specifically, there are five situations in which NSAIDs are not recommended:

1. Patients with nephropathy after massive sweating

2. Nephrotic patients who are using diuretics

3. Nephrotic patients who are taking pril/sartan drugs

4. Nephropathy patients whose hypertension control is not up to standard (140/90 mmHg or more)

5. Nephrotic patients with volume overload

In addition, NSAIDs were not recommended for patients with stage 4 nephropathy (renal failure, severe decline of renal function, glomerular filtration rate 15-30 ml/min, serum creatinine 443-707 umol/L). Recent studies have shown that moderate to severe renal failure can also be used, but the lowest effective dose should be used, and renal function should be monitored. If serum creatinine increases significantly, drug withdrawal should be considered.

If NSAIDs cause kidney damage, most of them can be reversed within 5 to 7 days after withdrawal. Patients with acute interstitial nephritis should be treated as soon as possible. It should be noted that if the renal function does not recover after one month, the renal damage in most patients will be irreversible.

NSAIDs are the main ingredient of many cold medicines, and are also recognized as the cause of chronic kidney disease and uremia. Cold medicine seems harmless to humans and animals, but it brings a greater risk to the above patients with kidney disease. During the use of cold medicine, renal function needs to be monitored.

Usually these kinds of kidney disease patients are not recommended to use, but relatively taboo, not absolute taboo. Nephropathy patients should consult nephrologists before using drugs (including all kinds of over-the-counter drugs) to prevent accidents. Maintain communication with doctors and regularly evaluate the need for discontinuation

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