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Individuals who have Kidney Disease may have no symptoms until kidney function has decreased to a very low level. It is of great importance to know the lab tests used to evaluate how well the kidneys are working. Here’s is a general introduction about the tests used to measure kidney function.
1、Creatinine Clearance (CrCl)
This is the most valid test of kidney function. It compares the creatinine in a 24-hour sample of urine to the creatinine level in the blood to show how much blood the kidneys are filtering out each minute.
Creatinine is a waste product that comes from the normal wear and tear on muscles of the body. Serum creatinine levels may vary depending on age, race and body size. The level rises when more than 50 percent of kidney function has been impaired.
3、Blood Urine Nitrogen (BUN)
A measure of the amount of nitrogen in the blood in the form of urea. A normal BUN level is 7~20. As kidney function decreases, this level rises.
4、Glomerular Filtration Rate (GFR)
It measures how well the kidneys are removing wastes and extra fluid from the blood. Normal GFR can vary according to age (as people get older, it can decrease). The normal value is 90 or above. If the value is below 60, this is a sign that the kidneys are not working adequately. A GFR level less than 15 indicates that renal replacement therapy such as dialysis or a Kidney Transplant will be needed.
A biopsy may be done occasionally for one of the following reasons:
▪ to identify a specific disease process and determine whether it will respond to treatment
▪ to evaluate the severity of kidney damage
▪ to find out why a transplant may not doing well
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