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An Overview of Lupus Nephritis: Cause, Risk Factor, Symptoms, Treatment, Test

2012-10-22 18:03

Lupus Nephritis is especially evident in most patients of Systemic Lupus Erythematosus (SLE), which usually arises within 5 years of diagnosis. However, more than half of patients feel no symptoms when they are diagnosed with Lupus Nephritis. Here, you can learn an overview of the disease.


Lupus Nephritis is a complication of SLE which is an autoimmune disease. Normally, the autoimmune system works to keep the body far away from infections or other harmful substances. However, in patients with autoimmune disease, the immune system fails to tell the harmful substances and native cells and tissues. Thereby, the failed immune system may attack the native organs, leading to various damages.

SLE (Systemic Lupus Erythematosus) can cause damages to different part of kidneys, leading to interstitial nephritis, membranous Glomerulonephritis and nephrotic syndrome etc. It may develop to Kidney Failure very soon.

Risk Factors

Gender. SLE is much more common in women than men.

Age. It is prone to appearing in people between the ages of 10~50.

Race. Africans and Asians are more easily affected than people from other races.

Drugs. Some drugs may affect your immune system and trigger lupus nephritis.


The symptoms of lupus nephritis may include one ore more of the following ones:

● foamy urine

● blood in urine

● high blood pressure

● frequent urination at night

● swelling in joints, feet and hands etc


The treatment of lupus nephritis will be individualized on the basis of the severity and other factors of your disease. Here are several available treatment suggestions for your reference.

● Diet. Manage a proper diet plan; keep the low level of salt, proteins and excess calories etc.

● Control blood pressure. Maintaining a stable blood pressure helps control the development of the disease.

● Focus on immune system. Immune system disorder is the root cause of lupus nephritis.

● Improve kidney functions. Treatment that helps repair the damaged kidneys, is very important to alleviate all symptoms and complications.

Test and Diagnosis

Tests for lupus nephritis not only include the conservative values, but also inflections of your immune disorder.

Tests that may be done include:

- blood and urine test

- test for lymphocyte subgroup

- test for complement in blood serum

- blood urine location

- test for toxins in blood

Diet and exercise change helps alleviate lupus nephritis. To stop the development of the disease, treatment for immune system and kidney tissues is necessary.

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