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Treatment for Membranous Lupus Nephritis

2013-02-07 16:29

Membranous lupus nephritis covers about 20% cases of kidney disease in lupus. While not so many patients with the condition will develop ESRD, it is associated with high incidence of complications. Therefore, membranous lupus nephritis should be treated early with aggressive treatment.

Supportive treatments

Cardiovascular and cerebrovascular events account for nearly 50% of deaths among patients with lupus nephritis.These problems should be managed aggressively. Both lupus and nephrotic syndrome are major risk factors of these events.

Diet, exercise and weight reduction are often used to treat hyperlipidemia. Specific lipid lowering agents are frequently required to treat the condition. ACE inhibitors and ARBs are classic medications for lowering high blood pressure and also they can reduce proteinuria.

Immunosuppressive therapies

Corticosteroids, azathioprine, alkylating agents are commonly used to treat membranous lupus nephritis. These drugs can suppress immune system and reduce the inflammation in kidneys. They can delay the disease progression to some extent, but some serious side effects are not inevitable.


Diet plays a vital role in controlling membranous Lupus Nephritis. As some foods can cause allergy, the patients should avoid eating those foods again. Also, if they have kidney damage, it is important to reduce the intake of proteins, sodium, etc. It is important to adjust their diet based on the levels of different types of minerals in blood.


Lupus is an autoimmune disorder which can involve kidneys and many other organs. The key point in treating membranous lupus nephritis is to correct immune dysfunction and prevent further attack to kidneys by immune system. Immunotherapy is featured with the above curative effects.

Immunotherapy is an advanced therapy for immune medicated kidney disease. It treats disease by enhancing or suppressing immune system to restore normal immune system. It can treat membranous lupus nephritis from its cause and stop its progression completely.

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