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Treatment for Lupus Nephritis with FSGS

Provided by Expert Zhang Youkang on 2013-05-27 16:52

Lupus nephritis is secondary to systemic lupus erythematosus (SLE) which is an autoimmune disorder.It is characterized by the inflammation of glomeruli, filters in kidneys.FSGS may occur in some cases of lupus nephritis. What is the treatment for lupus nephritis with FSGS?

Lupus nephritis with FSGS

In right condition,immune system can protect the body against foreign harmful substances.However,in lupus,the immune system attacks multiple body parts,resulting in inflammation in body.When the kidneys are involved, it will lead to lupus nephritis.

If the inflammation in kidneys is not controlled, it can lead to scarring and necrosis of glomeruli, resulting in FSGS. FSGS is very hard to control. If left uncontrolled, it may progress into Kidney Failure in few years.

What is the treatment for lupus nephritis with FSGS?

The principle goal of therapy in lupus nephritis is to normalize renal function or, at least,to prevent the progressive loss of renal function.It is important to treat extrarenal manifestations and other variables that may affect the kidneys.

Corticosteroid therapy is commonly used to treat lupus nephritis with FSGS.These drugs can suppress the abnormal immune response to reduce further damage to kidneys. Immunosuppressive agents may be used if the patients have an inadequate response or excessive sensitivity to corticosteroids.

Meanwhile,medicines are also needed to treat high blood pressure, hyperlipidaemia,hypoalbuminemia etc.These conservative treatments can slow the progression of lupus nephritis with FSGS, but can not stop the disease progression.

What is the alternative treatment for lupus nephritis with FSGS? To treat the condition effectively and fundamentally,the goals of treatment should include correcting immune dysfunction and restore the impaired glomeruli.The combined therapy of immunotherapy and Micro-Chinese Medicine Osmotherapy is an alternative treatment for lupus nephritis with FSGS. It can treat the disease fundamentally without relapses.

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