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Lupus with Stage 4 Kidney Disease Treatment


2013-07-26 14:00

Systemic lupus erythematous (SLE) is an autoimmune disease.With lupus, the immune system attacks its own body tissues by mistake.When kidneys are involved,it can result in kidney disease.Kidney disease is one of serious complications of lupus.Up to 60% of patients with lupus will develop Kidney Disease.In early stage,kidney disease usually develops asymptomatically so it often can not be noticed until serious kidney damage has formed.What is the recommended treatment for people with lupus and stage 4 kidney disease?

How does lupus impair kidneys?

While a healthy immune system produces antibodies to fight against bacteria and other infections,an autoimmune disease like lupus keeps antibodies from working properly.With lupus, the immune system fails to tell the harmful foreign substances from the body’s own healthy cells and tissues.As a result,the abnormal immune system attacks the healthy body tissues and lead to inflammation in different body parts.Kidney disease is a serious manifestation of lupus.If the inflammation can not be suppressed, it will cause progressive renal function decline.

In stage 4 kidney disease,the kidneys are damaged very seriously with glomerular filtration rate (GFR) of 15~29ml/min.A number of symptoms become present like proteinuria, high blood pressure, poor appetite and nausea, swelling etc.

Lupus with stage 4 kidney disease treatment

When chronic kidney disease (CKD) progresses into stage 4,Dialysis or kidney transplant will come soon.However,affective treatments can prolong kidney health and help the patients avoid them.

As mentioned above,lupus is an autoimmune disorder.Lupus nephritis results from abnormal immune response.Immunotherapy is a recommended treatment for lupus induced kidney disease.It can suppress the inflammation in kidneys and help the body rebuild normal immune system.By recovering the self-healing ability in body,it can stimulate the self-regeneration of impaired kidney tissues,thus enhancing renal function. In this way, the patients with lupus induced stage 4 kidney disease will be able to have a longer and high-quality life.


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