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Alternative Treatment for Stage 3 Lupus Nephritis to Cellcept


2013-08-27 16:41

Lupus nephritis refers to inflammation of kidneys caused by systemic lupus erythematosus (SLE),an autoimmune disease.Stage 3 lupus nephritis is also called focal lupus nephritis,in which less than 50% of the glomeruli,filters in kidneys are involved.Cellcept is often the first-line treatment for lupus nephritis,but is there any alternative treatment to it?

Stage 3 lupus nephritis

Lupus is an immunologically medicated disorder in which immune system attacks body tissues and cells by mistake.The abnormal immune system can cause inflammation in different body parts like skin, joints, nervous system etc. Kidney Disease is just a manifestation of lupus.

In stage 3 lupus nephritis, less than 50% of glomeruli, filters in kidneys become sclerotic. Clinically, hematuria and proteinuria is present, with or without Nephrotic Syndrome, hypertension, and elevated serum creatinine.

Cellcept for stage 3 lupus nephritis

Cellcept belongs to a kind of powerful immunosuppressive agents. It is commonly used to prevent organ rejection.In treating stage 3 kidney disease,it can suppress the abnormal immune system activity,thus suppressing inflammation in kidneys.It can slow renal function and decline and relieve some symptoms like proteinuria.However, the disease flares so frequently if it is only treated with Cellcept.

Alternative treatment for stage 3 lupus nephritis to Cellcept

As the underlying cause of lupus nephritis is abnormal immune system, the key treatment goal is to correct the immune dysfunction and recover normal immune system.

As in stage 3 lupus nephritis, a part of glomeruli are sclerotic.To improve renal function, another important treatment goal is to restore the impaired glomeruli.

The combined use of Micro-Chinese Medicine Osmotherapy and immunotherapy is an alternative treatment to Cellcept for stage 3 lupus nephritis.These two treatments can help the patients achieve the above treatment goals and make the patients get rid of the dependence on Cellcept and the frequent flares of the disease.




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