Hot Search:High Creatinine Level|Renal Failure|CKD|PKD |Dialysis

Diabetes is hard to manage. You can get a comprehensive understanding of the disease here and get the information about the latest treatments and get professional advices. read more

Micro-Chinese Medicine Osmotherapy is a brand-new therapy based on traditional Chinese herbal medicines dating back thousands of years ago. It combines the essences of herbal medicines read more

Hormonal therapy is commonly used to treat Kidney Disease in clinic. It refers to use one or more than one hormone medicines to suppress the over-reactive immune reaction read more

Patients are suggested to treat kidney disease first before they get pregnant read more

If you are diagnosed with Kidney Disease, you should talk to your doctor about starting an exercise read more

Foods and Drinks play an important role in Kidney Disease patients read more

Kidney Disease News and Events read more

In every week, a famous experienced renal medicine specialist will be invited to help diagnose and evaluate inpatient's disease condition, offering detailed therapeutic schedule. read more

Font Size A A A

Medullary Sponge Kidney

MSK basics


Medullary Sponge Kidney (MSK) is a congenital malformation of tubules-tiny tubes inside the kidneys. In right condition, urine flows through these tubules as it is being formed. However, in MSK, the formation of cysts growing in the medulla can affect the flowing of urine through the tubules freely.


Generally, in early stages of MSK, it causes no symptoms. Many patients do not develop symptoms until ages 30 to 40.

Urinary tract infection(UTI) and kidney stone are common and early symptoms of MSK. Meanwhile, the following symptoms usually occur subsequently.

* Burning or painful urination

* Vomiting and nausea

* Pain in the back, lower abdomen, or groin

* Hematuria

* Repeated urinary obstruction

* Hypercalciuria, increased oxalate concentration and tubular acidification defects


MSK is a birth defect featured with dilation of a collection duct. The dilation is caused by occlusion by uric acid during fetal life or results from tubular obstruction due to calcium oxalate calculi secondary to infantile hypercalciuria.


MSK is usually associated with a good prognosis. However, Renal Insufficiency can account for 10% cases among people with the disorder.

Renal Failure rarely occurs. But in rare cases, it may occur due to repeated pyelonephritis and or urinary tract infection. Therefore, controlling infection is very important to prevent kidney damage.


1.As Renal Insufficiency is mainly due to urinary tract infection and kidney stones. Therefore, the doctor usually recommends a treatment focusing on curing existing infection, removing any stones, and preventing future infection and stone formation.

2.The formation of cysts in medulla-the inner part of the kidney is attributable to kidney damage. Therefore, shrinking the cysts and preventing cysts from increasing in size and numbers is very important.

3. Repairing the impaired kidney structure and improving renal function is the key to prevent Renal Failure in MSK.

If you have been diagnosed with Medullary Sponge Kidney, we're here to help. Call us: +86-311-89261083 OR Email us: through Sunday) to make an appointment.

MSK symptom

Medullary Sponge Kidney is a congenital benign kidney disorder. It is featured with dilation of collecting tubules or more renal papillae. In the early stages, the patients usually do not develop symptoms. It usually is not diagnosed with until the second or third decade of life or later. With the disease progression, the patients will present the following symptoms.


Medullary Sponge Kidney is featured with recurrent calcium phosphate and calcium oxalate. Thus, occasionally, the patients can have recurrent nephrolithiasis, which can lead to significant morbidity. A patient is estimated to pass 1.23 stones per year.

2. Pyelonephritis and/or urinary tract obstruction

Pyelonephritis and/or urinary tract obstruction repeatedly among patients with Medullary Sponge Kidney. Urinary tract obstruction is mainly due to the formation of stone, but complete obstruction of the kidney by renal stones is rare. Further, it can affect the excretion of urine. As a result, the bacteria and virus may trigger pyelonephritis.

3. Pain

Some patients with Medullary Sponge Kidney may complain of severe, chronic renal pain in the back, lower abdomen, or groin without any manifestation of infection, stones, or obstruction.


Hematuria refers to loss of red blood cells in urine. It is commonly seen among people with Medullary Sponge Kidney. It results from frequent infections and kidney stone.

Fever and chills

Fever and chills are due to infections.

Renal insufficiency

Renal insufficiency is rarely seen. However, if urinary tract infection and nephrolithiasis are not controlled well, the risk of developing renal insufficiency will increase greatly.

The above is a general introduction about the symptoms of Medullary Sponge Kidney. If you have several of them, you should discuss it with your doctor and find out if it is associated with the disease.

If you have been diagnosed with Medullary Sponge Kidney, we're here to help. Call us: +86-311-89261083 OR Email us: through Sunday) to make an appointment.

MSK treatment

Medullary Sponge Kidney(MSK) is a congenital defect. The tiny cysts in medulla can block urine flow and cause a myriad of problems such as urinary tract infection, hematuria, kidney stone and even Renal Failure. The treatment involves resolving the complications of MSK and protect renal function.


In right condition, the urine flows from kidney into tubules and then is excreted out of body. When the urine does not flow properly, bacteria in the urine will be trapped in kidneys, leading to urinary tract infection and even kidney infection. To treat infections, antibiotics will be prescribed to control the infections.

Kidney stone

Kidney stone is a major risk factor for Medullary Sponge Kidney. If the stones can not pass from body, treatments should be adopted to break up the stones. Based on the types, locations and size of the stones, ESWL, shock wave, percutaneous nephrolithotomy, etc will be ordered by your doctor.

Asymptomatic adults with Medullary Sponge Kidney

When the adults with Medullary Sponge Kidney do not develop symptoms, they need not immediate treatment. However, they should take precautions to prevent possible renal calculi and urinary tract infection. Periodic urinalysis and abdominal radiograph is recommended to them.

Asymptomatic children with Medullary Sponge Kidney

In asymptomatic children with Medullary Sponge Kidney, it is necessary to conduct regular surveillance for Wilms tumor and other abdominal tumors.

The above are the main symptomatic treatment methods for Medullary Sponge Kidney. They can slow down the disease progression and reduce damage to kidneys effectively. However, if the patients' kidneys have been damaged seriously, those treatments alone will not be enough to control the disease at all.

If their kidneys are damaged seriously, high levels of toxins and wastes will build up in body. Therefore, filtering the harmful substances from body is a key step in preventing further kidney damage. Further, treatment should be used to rebuild kidney structure and improve renal function. In this way, Renal Failure will be avoided effectively.

If you have been diagnosed with Medullary Sponge Kidney, we're here to help. Call us: +86-311-89261083 OR Email us: through Sunday) to make an appointment.

MSK diagnosis

Medullary Sponge Kidney(MSK) is a birth defect featured by dilation of collecting tubules or more renal papillae. As it usually develops asymptomatically, it is usually found incidentally when examinations done for other problems. The following tests and procedures can help diagnosis of MSK.

Medical history

Typical presentations of MSK include flank pain, hematuria, recurrent urinary tract infection and renal stone. Meanwhile, the disorder is more common among people with the family history of Polycystic Kidney Disease, Chronic Kidney Disease, hemi-hypertrophy, Caroli's disease, etc.

Physical examination

Renal stone and UTI can cause pain in groin. If an obstruction with infection occurs, the patients may experience low blood pressure, high fever, increased heart beat. Also, blood in urine may occur due to kidney stone and infection.

Laboratory tests

Laboratory tests for MSK mainly includes urinalysis, renal function tests and tests for electrolytes. These tests are ordered in the workup for kidney stone, urinary tract infection, and pyelonephritis.

Urinalysis may reveal microscopic hematuria with or without kidney stone and pyuria. If the WBC increases, it implies infection( pyelonephritis).Analysis of stone composition provides information for preventive management.

Imaging tests

If you are suspected to have MSK, the following imaging tests usually are ordered by your doctor.


It is usually done if you have non-specific abdominal pain, or if urinary tract obstruction is suspected.


An x ray called intravenous pyelogram( IVP) may be ordered by the doctor to help confirm the diagnosis. In this test, a dye is injected into vein. It can show any blockage in the urinary tract. If cysts are present, they will show up as clusters of light in the IVP.

CT scan

CT scan can reveal papillary calcification or hyperdense papillae but usually is not as sensitive as excretory urography.

Helical CT scan

Helical CT scan is used to improve the definition of the abnormalities in Medullary Sponge Kidney.

The above are the main tests which are usually ordered to diagnose Medullary Sponge Kidney. If you are suspected to have the disorder, you should go for tests immediately.

If you have been diagnosed with Medullary Sponge Kidney, we're here to help. Call us: +86-311-89261083 OR Email us: through Sunday) to make an appointment.

MSK knowledge

▪ Sexual Life

Whether patients with Medullary Sponge Kidney can have sex depends on the severity of disease condition. In general, moderate sexual life is permissible as long as it will not aggravate the kidney function. It is necessary to discuss with your doctor about your specific condition.

▪ Pregnancy

Generally speaking, if women with Medullary Sponge Kidney do not have serious kidney damage, they can have a healthy pregnancy. However, some disorders can make the pregnancy difficult.

1. Infections and kidney stones are two major problems the women may encounter during their pregnancy. When these occur, they may cause extreme pain.

2. If women with Medullary Sponge Kidney have developed serious Renal Insufficiency, they are not recommended to get pregnant. It will certainly put extra strain on her kidneys, thus aggravating renal function. Creatinine level under 1.1 mg/dl and creatinine clearance rate above 70ml/min are safe for pregnancy.

3. If Medullary Sponge Kidney is complicated with high blood pressure and the blood pressure is out of control, it will increase the risk of pregnancy because it can increase the incidence of preeclampsia which is harmful to both mom and baby. Therefore, the women with Medullary Sponge Kidney are recommended to reduce their blood pressure to 140/90 mmHg.

If the above risk factors of pregnancy can be controlled very well, the women with Medullary Sponge Kidney will have a healthy baby.

If you have been diagnosed with Medullary Sponge Kidney, we're here to help. Call us: +86-311-89261083 OR Email us: through Sunday) to make an appointment.

MSK healthcare

Medullary Sponge Kidney is a disorder that retains fluids in the ducts of your kidneys. While diet and exercise won't cure the disease, it can slow down its progression and improve its prognosis remarkably.

1. Drink more water

Kidney stones are major and serious symptoms of Medullary Sponge Kidney. To reduce the risk of developing stone, you are recommended to drink 8 ounces of water within 1 tablespoon of backing soda twice a day. You should no reply on over the counter anticids because they have to be filtered out of body kidneys and increase strain on kidneys.

2. Keep a organic diet

You should stick to an all organic diet. As you are diagnosed with Medullary Sponge Kidney, your kidneys fail to filter out toxins from body adequately. Therefore, it is important for you to cleanse your system. A organic diet can help. Meanwhile, you can take cleansing dietary supplements, relax in a sauna or steam room to sweat out your toxins, etc.

3. Foods low in oxalate

Oxalate is an major source of kidney stone. It is a wise option to limit the consumption of foods high in oxalate such as spinach, rhubarb,peanuts and Swiss chard. Foods that help prevent kidney stone formation mainly include foods, vegetables and grains that are rich in fiber.

4. If you are suffering from kidney stones, it is difficult to do exercise. Because the stone can cause pain when they are moving. However, proper exercise can help pass stone. You are recommended to drink a large amount of liquid. And then after 20 minutes, you run up and down stairs vigorously. This can help small and stubborn kidney stones to pass naturally.

Additionally, walking, toe touching, sit-ups, and push-ups also can be done by the patients with Medullary Sponge Kidney and they are beneficial to pass stone.

If you have been diagnosed with Medullary Sponge Kidney, we're here to help. Call us: +86-311-89261083 OR Email us: through Sunday) to make an appointment.

contact us
medullary Sponge Kidney
patient story

Latest Articles