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Factors that Affect Prognosis of Glomerulonephritis

Provided by Expert Zhang Youkang on 2013-04-18 13:56

Glomerulonephritis is a kidney disorder in which the filtering units are impaired.This condition may be temporary and reversible,or it may get worse.What factors can affect prognosis of glomerulonephritis?

How is the prognosis of glomerulonephritis?

Progressive glomerulonephritis may lead to chronic kidney failure, reduced renal function and end stage renal disease (ESRD).The prognosis is mainly affected by the following variables.

Pathological type

There are various types of glomerulonephritis such as thin basement membrane disease, minimal change glomerulonephritis,focal segmental glomerulosclerosis(FSGS),membranous glomerulonephritis,IgA Nephropathy,etc.The kidney damage degree varies in different pathological types so the prognosis of glomerulonephritis is also different.


If you have Nephrotic Syndrome and it can be controlled, you may also be able to control other symptoms.If it can not be controlled, you are at high risk of developing ESRD.Nephrotic syndrome is an important factor in worsening prognosis of glomerulonephritis.Additionally,high blood pressure and proteinuria also can affect the long-term outcome of the disease.


Immunosuppressive and cytotoxic drugs are commonly used to treat glomerulonephritis.Long-term use of these drugs can increase infection, osteoporosis,Diabetes,and hypertension. These complications can worsen the long-term outcome of the disease.What’s worse,these treatments just aim at controlling the symptoms of the disease, but can not eliminate the causes. So they are not enough to stop the disease progression and reverse kidney damage.

No matter what disease you have,early inspection and treatment play the key role in affecting the prognosis of the disease.Early aggressive treatment can reverse kidney damage and stop further renal function decline completely.

Immunotherapy can treat glomerulonephritis by eliminating the triggering factors of kidney impairment and activate the self-healing system of the body.It can stop further kidney damage and bring an improvement of renal function.Thereby,the prognosis of glomerulonephritis will be improved remarkably.Apart from immunotherapy, there is an alternative way to treat glomerulonephritis.

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