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Tests and Diagnosis of Nephritis

Provided by Expert Zhang Youkang on 2012-10-02 09:23

Nephritis is often diagnosed by evaluating a patient's history and specific signs and symptoms. If the doctor suspect this disease, lab tests may also be ordered to make a diagnosis of Nephritis.

Urine test. A urine analysis may show red blood cells or red blood casts in the urine, which indicates the possible damage to the glomeruli. This test may also show white blood cells (indicator of inflammation) and increase protein (indicator of nephron damage).

Blood tests. These can provide information about damage of the kidneys and the glomeruli by measuring levels of wastes like creatinine and BUN.

Imaging tests. After detecting the evidence of damage, the doctor may recommend imaging test such as a kidney X-ray, an ultrasound examination or a CT scan.

Kidney biopsy. A biopsy involves using a special needle to extract small pieces of renal tissue for microscopic examination to help determine the cause of the inflammation. It is necessary to confirm the diagnosis of Nephritis.

The above is a general introduction of the conventional diagnosis of Nephritis. To make an accurate diagnosis of the disease, more special tests are also needed to guide the treatment. With the help of these tests, patients can understand their conditions clearly. Special tests include:

▪ Kidney Damage Tests. Aims: 1) confirm the kidney damage; 2) the damaged part, glomerulus or renal tubules; 3) make the severity of kidney damage clear and guide the clinical choice of medicine; 4) judge patient's sensitivity to medicines and guide the clinical medicine application.

Checking items include: UTP, U-malb, U-TRF, U-IGG, β 2-microglobulin, α1-microglobulin, α2-macroglobulin, κ light chain, λ light chain, U- NAG, U-GGT, and Uosm.

▪ Toxins in Blood Tests. Aims: 1) Make the buildup of toxins in the body clear; 2) guide the choice of immune clearance method.

Checking items include: BUN, Creatinine, UA, β 2-microglobulin, Cyc C, RBP, HCY, and PTH.

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