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Nephritis basics

What is Nephritis?

Nephritis refers to inflammation of one or both of the kidneys. It can be caused by infection, but is most commonly caused by autoimmune disorders that affect the major organs. It can rarely be generically inherited, though the disease may not present in childhood.

Nephritis resolves completely in about 60% of adults and 90% of children, for many it comes and goes with little disruption to their life. However, for those whose disease doesn't get better and instead progresses into more serious condition, advanced kidney failure may have developed before they have had any reason to seek medical help.

Causes and risk factors of Nephritis

Nephritis may occur due to a number of factors including auto-immune disorders, infections, and other diseases. Usually, people develop Acute Nephritis after they have suffered from ailments like strep throat, rheumatic fever, and scarlet fever.

·For 5% of men who end up with kidney disease, the disease can be hereditary.

·Streptococcus bacteria often causes some damage to the kidney's filtering units, which lead to children's and even adults' getting Nephritis.

· Adult Nephritis may be caused by pneumonia, vasculitis, or the inflammation of a person's blood vessels, mumps and hepatitis. In certain cases, abscesses can also be the reason.

·Other causes also include gout, yellow fever, typhoid fever, renal tuberculosis, Hermann's syndrome, immune complex disease, and urethral stricture.

·Certain medicines and certain poisons.

·Metabolic disorders.


Factors that may affect the prognosis of Nephritis include:

·Pathological factors. 1) Pathological types: prognosis of mild Mesangial Proliferative Nephritis is good, while severe Mesangial Proliferative Nephritis, Membranous Proliferative Nephritis, and FSGS have bad prognosis. 2) The more the number of fibrous crescents, sclerosed glomerulus, interstitial fibrosis and renal tubules atrophy, the outcome is worse. 3) Patients with serious renal vascular diseases have unfavorable outcome.

·Clinical manifestation. The prognosis is not good if patients experience symptoms including: persistent massive proteinuria and persistent hematuria, uncontrollable high blood pressure, and renal tubular-interstitial injury (such as renal anemia, increased urine output at night, Fanconi syndrome, renal tubular acidosis, etc).

·Dietary factor. High protein diet may accelerate the progression of Nephritis.


·Avoid triggers that cause Nephritis. Since streptococcus bacteria is one of them, people need to avoid getting strep throat by also avoiding people who has this ailment.

·Live a healthy lifestyle that includes regular exercise, proper diet, and ample rest. Once the immune system is solid, persons won't have to fear certain infections that may lead to Nephritis.

·Drinking lots of water and constantly discharging urine, which help keep the bladder clean and help people avoid this ailment as well.

·Take positive treatment of various primary diseases like high blood pressure, Diabetes, etc. These disease may aggravate renal tubule arteriosclerosis and glomerular sclerosis so as to cause Nephritis. Control infections effectively, especially infections of the urinary tract and respiratory tract.

·Protect oneself against cold or flu. Reduce the risk of getting this ailment. Avoid being tired. Do not take medicines that may harm the kidneys.

If you have been diagnosed with Nephritis, we're here to help. Call us: +86-311-89262207 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

Some common signs and symptoms of Nephritis include:

·Puffiness in the face, and swelling of the feet and ankles, around the eyes, and legs.

Nephritis symptoms

·Decreased urine volume

·Dark urine

·Pain in the kidneys

·Rise in the blood pressure



·Visual disturbances

·Tiredness and general malaise

·Nausea, and/or vomiting

·Joint pain

·Loss of appetite

If you have one or more of these symptoms, it does not mean you have Nephritis. However, it is important to discuss any symptoms with your doctor. They may indicate other health problems.

If you have been diagnosed with Nephritis, we're here to help. Call us: +86-311-89262207 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

Nephritis treatment

Treatment for Nephritis depends on the type and cause of the condition. The goal is to reduce inflammation, limit the damage to the kidneys and treat complications, and replace lost kidney function.

Conventional treatment

·Limit the intake of salt, potassium, protein and fluids in the diet.

·Steroids, or more powerful immunosuppressant drugs may be given to reduce the inflammation.

·Antibiotics may be needed to control infection.

·Anti-hypertensive medicines are used to control blood pressure.

·In severe cases, dialysis may be necessary.

·End-stage renal disease (ESRD) patients may consider undergoing a kidney transplant.

Latest treatment for Nephritis - Immunotherapy

Current immunology study shows that most of the kidney diseases (>95%) are caused due to immune dysfunction, so is Nephritis. Immune dysfunction means that there is immune system abnormality within kidney disease patient's body. Therefore, only if the immune system get regulated, various diseases can be treated effectively from the root.

Nephritis is a kind of immune disease. If one's immunity is low, it is very likely to cause immune disorder after getting a fever or infection. The immune disorder will cause over reaction of immune system. The immune complex will stay in blood circulation and deposit in the kidneys.

During the process of removing these immune complexes, the immune response becomes more and more tense, eventually leading to hypersensitivity. Normal renal intrinsic cells and healthy tissues may be damaged by hypersensitivity.

Treating Nephritis with Immunotherapy involves six steps:

Step 1: Scientific tests.

Step 2: Blocking immune reaction.

Step 3: Immune tolerance.

Step 4: Immune regulation.

Step 5: Immune protection.

Step 6: Immune clearance.

As a holistic therapy, Immunotherapy is one of the best treatments of Nephritis. It focuses on the regulation of overall immune system, so the disease can be treated from the root without further relapse.

If you have been diagnosed with Nephritis, we're here to help. Call us: +86-311-89262207 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

Nephritis diagnosis

The diagnosis of Nephritis should take into consideration the symptoms and potential underlying causes of this type of kidney inflammation. Doctors will often ask questions about a full medical history and family history (of certain auto-immune conditions like lupus).

A variety of laboratory tests can also be used to inform the diagnosis. The tests may include:

·Throat swabs - presence of streptococcal bacteria, which may be responsible for acute cases of the condition;

·Check blood and urine samples for signs of inflammation - increased protein or blood cells in urine and a buildup of urea in the blood.

·Iothalamate clearance testing - show that how fast the kidneys are filtering waste.

A kidney biopsy is needed if the above tests are inconclusive. Doctors will extract a small sample of kidney tissue using a needle. It is usually performed on an outpatient basis. Doing this test allows a doctor direct access to the inflamed tissue, which can lead to a more conclusive Nephritis diagnosis.

On the basis of the information gained through testing, doctors can be able to make a final diagnosis and corresponding treatment plan.

Usually, Acute Nephritis is highly treatable with antibiotics and anti-inflammatory drugs, while Chronic Nephritis can sometimes be managed with medicines and by following a special diet plan.

If you have been diagnosed with Nephritis, we're here to help. Call us: +86-311-89262207 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

Nephritis knowledge

Nephritis has many variations - a kidney inflammation caused by infection, autoimmune disorder or poison- the treatment tends to be similar for all varieties. Once diagnosed with this disease, patients need to pay attention to the following aspects in their life.


For people with Nephritis who are unmarried, they are not suggested to get married before the healing of the disease, because the sexual life or pregnancy after marriage may cause relapse of the disease, thus aggravating the illness condition and damage of kidney function.

In general, patients should not get married until the disorder is cured in clinic. Clinical cure means that all of symptoms have disappeared, both the renal function and urine test result are normal, and the disease doesn't recur within two years.

Sexual Life

▪ Be abstemious about sexual life. People who have Acute Nephritis, acute period of Chronic Nephritis, and unstable disease condition should not have sex in order to avoid further deterioration.

▪ Basically, patients in the active period of Nephritis or with Renal Failure should not have sex. For those who are in the recovery stage of Chronic Nephritis and have stable condition can have moderate sexual life. Never be excessive.

▪ Individuals of middle or advanced stages of kidney disease should strictly control the sex activity by reducing the frequency and length of having sex.

▪ The application of medicine treatment (such as certain antihypertensive drugs) may affect the quality of sexual life.

▪ Pay attention to the hygiene of sexual life. Clean genitals before and after having sex in order to avoid urinary tract infection, which may aggravate the disease condition.


Whether people with Nephritis can get pregnant depends on the severity of kidney disease. Patients who have basically normal kidney function and few urine protein (microscale or +) for a period of time can consider being pregnant. However, people with conditions as below should not be pregnant:

▪ Chronic Nephritis accompanied with increased blood pressure. In this case, if patients get pregnant, about 75% of them will develop severe pregnant high blood syndrome, leading to premature birth or even stillbirth.

▪ Chronic Nephritis accompanied with abnormal kidney function, massive proteinuria ("++" or "+++"), high BUN or creatinine.

Besides, pregnant women with Nephritis need to ensure enough rest and nutrition so as to enhance the body's resistance and avoid various infections. Regular check-ups are also necessary. The most important point is that people with Nephritis should seek for a systematic and effective treatment for their diseases. With good recovery, they can give birth to a healthy baby.

If you have been diagnosed with Nephritis, we're here to help. Call us: US +86-311-89262207 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

Nephritis health-care

When patients need to get well with Nephritis, following a healthy lifestyle is one of the important things they will need to do. Here are some suggestions:

· Eat the right things.

This may help expedite the healing process. 1) Avoid oxalic acid that can be found in spinach, chocolates, rhubarb, and other cocoa products. 2) Have an all-vegetable juice diet for a few days, which should help clean the bladders and remove any toxins that may be causing the disease. 3) Adopt a healthy attitude towards meals. Eat more high-fiber vegetables and fruits. 4) Cut out the intake of salt, while increase the fluid intake.

·Ensure to have ample rest.

People in the acute episode stage or accompanied with symptoms like high blood pressure and edema should have ample bed rest. They can increase their physical activities when the disease condition becomes stable. Avoid being tired. Women with Nephritis are not suggested to get pregnant because pregnancy may aggravate the illness, and even lead to the relapse of the condition.

·Take good care of the skin.

Patients with severe edema need to pay attention to the skin care. Wear cotton clothes and change them frequently. For those who stay in bed for long time, they need to avoid the occurrence of bed sore.

·Observe the changes of illness condition.

Do regular urine tests. Do not neglect the occurrence of early Uremia symptoms like headache, loss of appetite, nausea and vomiting, decreased urination, etc. Go to see a doctor if there is abnormal changes of urine output.

·Exercise properly and strengthen the physique. Keep balance between work and rest.

·Avoid medicines that may harm the kidney. Control blood pressure well and avoid the deterioration of kidney damage.

If you have been diagnosed with Nephritis, we're here to help. Call us: US +86-311-89262207 OR Email us: kidneyabc@hotmail.com(Monday through Sunday) to make an appointment.

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