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Treatment for FSGS and Nephrotic Syndrome

2013-02-04 13:48

Focal segmental glomerulosclerosis (FSGS) is a kidney disorder in which the kidney's filtering system (glomeruli) is damaged. It is one of the causes of a serious condition known as nephrotic syndrome.

Each person has two kidneys.There are millions of tiny, microscopic filters in the kidneys called glomeruli. They can filter blood and take excess fluids and wastes out of body by producing urine. Meanwhile, they can leave the protein in the blood. In FSGS, the glomeruli become scarred. As a result, the proteins start leaking into the urine instead of staying in the blood. Increased permeability of glomerular filtration membrane and heavy protein in urine can cause nephrotic syndrome.

Steroid therapy is used to treat Nephrotic Syndrome and FSGS most commonly. Prednisone is often given to control proteinuria. Additionally, the following treatment recommendations are usually given:

* Immunosuppressive agents to suppress the immune system

* Diuretics and low-salt diet to help control retention of fluids

* ACE inhibitor to control blood pressure and lower protein in urine

* Anticoagulants to prevent blood clots

* Anticoagulants to prevent blood clots

* Stains to lower the cholesterol level

* A healthy diet low in salt and fat

* Quit smoking

The above treatments can help control the symptoms of FSGS and slow down the progression of the condition. However, they are not enough to stop the disease progression. If no other aggressive treatment is used, the condition can progress into renal failure very rapidly.

What is the alternative treatment for FSGS and nephrotic syndrome?

FSGS is an immunologically mediated disorder. It means that the immune system lose its normal protective function, but attacks the healthy kidney tissues in body mistakenly. As a result, the filtering units in kidneys are damaged. Therefore, to treat FSGS and nephrotic syndrome effectively, the treatment goal should be correct immune dysfunction and restore the impaired kidney tissues. Immunotherapy is an alternative treatment for FSGS and nephrotic syndrome. This therapy has the above curative effects and can bring a good treatment outcome.

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