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Latest Treatment for Nephrotic Syndrome in FSGS


2013-03-04 09:34

FSGS is an immunological disorder in which the kidney tissues are scarred. It is one of common causes of Nephrotic Syndrome characterized by heavy proteinuria, swelling and hyperlipidaemia.

Nephrotic syndrome can accelerate the renal function deterioration significantly. If heavy proteinuria can not be controlled, FSGS may develop into Kidney Failure in few years. Therefore, it is important to treat nephrotic syndrome aggressively early enough.

Routine treatments for nephrotic syndrome mainly include steroids, antihypertensive medications, diuretic etc. These drugs can relieve the symptoms of the condition respectively, but are not enough to eliminate the causes of FSGS. Although the patients can have a remission after weeks’ steroid treatment, the disease is very likely to relapse. Thereby, the patients with the condition are seeking for alternative treatment eagerly. To treat nephrotic syndrome in FSGS effectively from its causes, the first step is to find out the causes of the condition.

How does nephrotic syndrome occur in FSGS?

The general cause of FSGS is immunological. The immune system fails to protect the body, but attacks the kidney cells by mistake. As a result, the abnormal activity of immune system will cause the inflammation in kidneys, leading to scarring and sclerosis of the kidney tissues. When the filters called glomeruli can not function adequately, the proteins in blood will pass through the filters and end up in urine. Massive protein in urine can cause nephrotic syndrome.

What is the latest treatment for nephrotic syndrome in FSGS?

Just as mentioned above, the routine treatments are an essential part of nephrotic syndrome treatment.

Immunotherapy is the latest treatment for nephrotic syndrome in FSGS. It treats disease by utilizing the autoimmune immune system. In treating FSGS, it can suppress the abnormal activity of immune system to stop more immune damage to kidneys. Thereby, it can stop the relapse of the condition.

Additionally, it can activate the self-healing ability of the kidneys to repair the impaired kidney structure and improve renal function. By doing this, the leakage of proteins will be controlled. As the causes are eliminated, nephrotic syndrome in FSGS will be controlled fundamentally.


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