Prednisone is a kind of common drug option for nephrotic syndrome in children.If the children response to the medicine,they will have a remission.
How does prednisone treat nephrotic syndrome in children?
In right condition, the immune system general antibodies to attack foreign stuffs called antigens.However,in nephrotic syndrome,the immune system does not work well and it attacks the body’s cells mistakenly, resulting in inflammation in kidneys.
Prednisone interferes with the working of the immune system and suppress the abnormal activity of immune system. So the children will have a remission after a period of treatment. However, prednisone can not correct the immune dysfunction so nephrotic syndrome in children will relapse whenever there is a triggering factor.
What is the possible adverse effects of the drug on body?
*More vulnerable to infection:Prednisone not only can suppress the abnormal immune system, but also can weaken the normal immunity. It make the patients more vulnerable to infection.
*Mood swing: Stress, sudden anxiety, depression, restlessness etc may be experienced by children with nephrotic syndrome.
*Weight gain:Weight gain is one of the most common side effects of consuming prednisone. Prednisone can improve the appetite, thus resulting in weight gain and deposition of fat.
* Osteoporosis: Prednisone can reduce the development of new bone cells, thus reducing bone density and weakening them.The bone will become fragile,which can inhibit the development of the children.
Apart from the above side effects of prednisone,hormonal changes, eye problems,diabetes are also can be seen in children with Nephrotic Syndrome.
Given the above adverse effects, the parents whose child is suffering nephrotic syndrome are eager to find alternative treatment for nephrotic syndrome in children.
For the causes of relapse of nephrotic syndrome in children, to control the disease completely, the patients should choose treatment to correct their immune dysfunction. Immunotherapy is an alternative treatment for the condition. It can correct immune dysfunction and help rebuild the normal immunity.Thus, it can prevent of nephrotic syndrome in children and stop the disease progression.