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Will All People with PKD Develop Renal Failure

2012-11-23 16:04

Polycystic kidney disease(PKD) is a genetic disorder. As there is no cure for it, many patients worry if they will develop renal failure. In fact, not all people with the condition will develop renal failure as its prognosis is attributed to variables.

About 50% of people with PKD will have renal failure by age 60, and about 60% will have renal failure by age 70. People with renal failure will need dialysis or a kidney transplant to prolong their life. Certain people have an increased risk of renal failure including:

High blood pressure

High blood pressure is a major risk factor in aggravating renal function. It is due to the pressure of growing cysts to nephrons.

Protein or blood in their urine

Blood in urine is mainly due to rupturing of cysts and cyst infections. Generally, if proteinuria is above 1g/d, it indicates a poor prognosis.


Men with PKD are at higher risk of developing renal failure.


Women with high blood pressure who have had more than three pregnancies

The above are the major risk factors in affecting the prognosis of PKD. If they can be controlled very well, it can reduce the risk of developing renal failure significantly.

Additionally, what really matters in influencing its prognosis is the treatment for PKD.

Routine test along with new treatment can give a better prognosis of PKD and reduce the risk of developing renal failure. Routine treatments are mainly used to control the symptoms of PKD and new treatment named Micro-Chinese Medicine Osmotherapy can stop the cysts from enlarging and shrinking the large cysts. The combined application of the therapies can give the patients a better outcome and prevents PKD from progressing into renal failure.

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