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Uncontrolled polycystic kidney disease( PKD) can give rise to myriad of complications such as high blood pressure, back pain, hematuria etc. Is there a link between polycystic kidney disease and osteoporosis?
Kidneys perform important functions in our body.Remove waste products from the body.Balance the body’s fluids.Produce an active form of vitamin D that promotes strong, healthy bones. If the diseased kidneys can not function normally, the levels of calcium in body will reduce, thus resulting in osteoporosis.
Polycystic Kidney Disease develops very slowly and symptoms usually start to appear between age 30~40. In early stage, if the cysts are not big enough, they can not affect the normal renal function. So if osteoporosis occurs in early stage of polycystic kidney disease, there may not be a link between these two conditions.
However,if the cysts keep enlarging persistently,they will take over more and more healthy kidney tissues,leading to kidney failure eventually. The diseased kidneys fail to remove phosphorus from body. High levels of phosphorus in blood can cause loss of calcium from bone.Additionally, as the patients with Kidney Failure usually develop digestive system problem, it can affect the absorption of calcium from foods.
Whether osteoporosis is related to polycystic kidney disease depends on the kidney damage degree.
Apart from osteoporosis,polycystic kidney disease may also cause the following symptoms and complications.
High blood pressure:High blood pressure is often the first sign of polycystic kidney disease.It occurs when the enlarged renal cysts compress the surrounding kidney tissues. The pressure can affect the production of hormones which can regulate blood vessels, thus resulting in high blood pressure.
Back or side pain: Back or side pain is due to the pressure to other organs or stretching of renal capsule. Usually, the pain is mild. However, if the back is caused by rupturing of cyst, the pain will become extremely intense.
The above article introduces the relationship between polycystic kidney disease and osteoporosis. If you are interested in other aspects of the disease, please email to firstname.lastname@example.org.