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Drug Information on Polycystic Kidney Disease

2013-11-21 11:18

Drug Information on Polycystic Kidney DiseasePolycystic kidney disease(PKD), one of the most common human genetic diseases, is characterized by massive enlargement of fluid-filled renal tubules and collecting duct cysts which will cause end stage kidney failure. PKD is a serious and costly disorder. There is no available therapy that prevents or slow down the cystogenesis and cyst expansion in PKD. But its symptoms can be treated by some drugs. Here are some common drug information on PKD. Hope it can help you.

Whatever dugs you take, the goal of treatment is to control symptoms and prevent complications.

-High blood pressure

High blood pressure may be hard to control, but controlling it is the most common important part of treatment. The drugs of choice for this condition are angiotensin-converting enzyme (ACE) inhibitors (i.e, captopril, enalapril, lisinopril), angiotensin II receptor blockers (ARBs)(i.e, telmisartan, losartan, irbesartan), calcium antagonists(i.e, nifedipine, nimodipine, nitrendipine), diuretics(i.e, hydrochlorthiazide, chlorthatidone, spironolactone).


Pain is a common symptom of PKD. If it is mild, you can control it with over-the-counter medications containing acetaminophen. If it is more severe and constant, surgery is recommended to remove the enlarged cysts.

-Urinary tract infection

It is best to promptly treat infection that may develop. Long-term antibiotic treatment may be needed to treat infection, such as ciprofloxacin, trimethoprim-sulfamethoxazole, clindamycin, and chloramphenicol.

-Blood in urine

Blood in urine usually results from cyst rupture. It is necessary for you to drink lots of water as soon as you notice blood in your urine, in order to dilute the urine. Bed rest also may help decrease the bleeding. If the bleeding lasts for several days, hospitalization is necessary.

The above drugs referred to are almost western medicines. Though they can control the symptoms and complications of PKD, it is just temporarily, because they can not improve kidney function from the root. For PKD patients, how to control these cysts is the key. Maybe the natural Chinese herbs are a good choice.

The information is limited, if you would like to know more, you can leave us a message or email to kidneyabc@hotmail.com.

If you send us email, please leave your phone number or WhatsApp/Viber (with country code) in email so that our renal expert can communicate with you timely and directly. We will do utmost to help you solve the problems.

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