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How to Prevent Relapse of Henoch-Schonlein Purpura Nephritis (HSPN)


2013-01-06 14:29

Henoch-Schonlein purpura (HSP) can involve the systemic small blood vessels. If the tiny blood vessels in kidneys are involved, it will cause Henoch-Schonlein purpura nephritis. In most cases, purpura nephritis has a good prognosis. However, if the condition relapses frequently, it can aggravate renal function decline and progression into renal failure. Therefore, it is important to prevent relapse of Henoch-Schonlein purpura nephritis effectively.

HSP is an immunological disorder characterized by IgA deposits and other immune complexes small blood vessels. To eliminate the immune deposits in kidneys, an inflammation is activated, which can lead to immune damage to kidneys.

Conventionally, steroids, cyclophosphamide and prednisone are used to treat Henoch-Schonlein purpura nephritis. However, clinical evidence shows that these treatments can not decrease the likelihood of developing long-term kidney disease and relapse of Henoch-Schonlein purpura nephritis. Conventional drugs and treatments only can suppress the inflammation in kidneys to alleviate the associated symptoms. However, they are unable to eliminate the immune deposits in tiny blood vessels of the kidneys.

To prevent the relapse of Henoch-Schonlein purpura nephritis, the therapy should be able to suppress the inflammation in kidneys and eliminate the immune deposits in kidneys completely. Immunotherapy is recommended to the patients with Henoch-Schonlein purpura nephritis.

This therapy treats disease by adjusting the autoimmune system. As for the treatment of Henoch-Schonlein purpura nephritis, it can suppress the inflammation in kidneys effectively and rapidly, thus preventing further damage to kidney tissues and cells. Moreover, it can regulate immune system to prevent formation of immune complexes which are trigging factor of the disease relapse. Finally, immunotherapy can control the symptoms of Henoch-Schonlein purpura nephritis by restoring the impaired tiny blood vessels and improving renal function.

As immunotherapy can treat Henoch-Schonlein purpura nephritis from its root causes, it can give the patients a good recovery without relapse.



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