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Kidney Damage Tests


2014-03-27 13:20

The appearance and smell of your urine—as well as the frequency with which you have to go—can provide many clues to what else is going on in your body. And the urine content will help to find the very early alarm of kidneys. The tests are most often performed, when you are at the risk to develop any kidney damages.

What are the tests for kidney damages?

Tests for kidney damages focus on the content of urine, which totally include 12 indexes as follows.

- U-TP (Urinary Total Protein). A urine total protein test is conducted to detect excess protein in the urine. When U-TP>150mg/L, kidney problems may be expected.

- U-malb (Urinary Microalbumin). Microalbumin indicates the early damages to glomerular mechanical barrier. The normal reference is Umalb≦30mg/L.

- U-TRF (Urinary retinol binding protein). U-TRF indicates the early damages to glomerular charge barrier. The normal reference is Umalb≦1.9mg/L..

- U-IgG (Urinary Immunoglobulin G). Large amount of U-IgG tells that glomerular filtration membrane is damaged seriously. The normal reference is Umalb≦8.8mg/L.

- Uβ2-M (Urinary β2-Microalbumin). The characteristics of beta2 microglobulin (B2M) make it useful as a tumor marker for some blood cell cancers, for detecting kidney damage, and for distinguishing between glomerular and tubular disorders of the kidney.

- Uα1-M (Urinaryα1-Microalbumin). It indicates the reabsorption of renal tubules, which is a better reference than B2M in most conditions.

- α2-M (Urinaryα1-Macroalglobulin). Its appearance indicates postrenal proteinuria.

- light chainκis always the marker of prerenal proteinuria which is a common symptom of light chain disease, multiple myeloma, lymphoma etc.

- light chainγhas a similar function of light chain γ.

- U-NAG (Urinary N-acetyl-beta-D-glucosaminidase). Urinary concentration of NAG is a sensitive index of renal tubular function.

- U-GGT (Urinary Gamma-glutamyl transpeptidase). Urinary concentration of NAG is a sensitive index of renal tubular function.

- Urinary Osmotic Pressure. It is a smart index to reflect the concentration and dilution function of renal tubules.

Why choose  the tests for kidney damages?

It helps your doctor make an overview about your kidney medical condition, including:

● whether your kidney are injured or not

● Which part of your kidney are injured, glomeruli or renal tubules?

● How severity is your kidney damages? The tests offer directions for your doctor to choose drugs for you.

● The tests find your sensitivity to current drugs and are the basis for your doctor to consider drug changes for you.



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