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Special Tests for Focal Segmental Glomerulonephritis

2012-09-16 17:17

▪ Kidney Damage Tests. Aims: 1) confirm the kidney damage; 2) the damaged part, glomerulus or renal tubules; 3) make the severity of kidney damage clear and guide the clinical choice of medicine; 4) judge patient's sensitivity to medicines and guide the clinical medicine application.

Checking items include: UTP, U-malb, U-TRF, U-IGG, β 2-microglobulin, α1-microglobulin, α2-macroglobulin, κ light chain, λ light chain, U- NAG, U-GGT, and Uosm.

▪ Urinary protein electrophoresis. This test is used to analysis the composition of urine protein. Aims: 1) judge the source of proteinuria; 2) make differential diagnosis of various kidney diseases; 3) determine patient's drug susceptibility.

▪ Selective urine protein index (SPI). Aims: 1) determine the type of glomerular diseases; 2) judge the prognosis; 3) guide the medicine application in clinic.

SPI≤0.1 indicates high selective proteinuria, slightly glomerular damage, the treatment effects of hormones and immunosuppressants are good, prognosis is mostly favorable (mostly seen in MCD);

SPI>0.2 indicates non-selective proteinuria, serious glomerular damage, the treatment effects and prognosis may be unfavorable (MN, FSGS).

▪ Complement in Blood Serum Tests. The tests include C3, C4, CH50, C3B etc. They serve to help your doctors to hold a clear overview of classical pathway and specific pathway of complement, which can deal with the underlying immune disorder.

▪ Toxins in Blood Tests. Aims: 1) Make the buildup of toxins in the body clear; 2) guide the choice of immune clearance method.

Checking items include: BUN, Creatinine, UA, β 2-microglobulin, Cyc C, RBP, HCY, and PTH.

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